Use of Bioequivalence Tests and Its Properties under Different Sampling Techniques
Faryal Basharat, Nasir Jamal, Muhammad Hanif, Usman Shahzad
Asian Journal of Advanced Research and Reports · pp. 36–45 · Published 6 Jul 2020
10.9734/ajarr/2020/v11i430275Abstract
Bioequivalence testing is the initial approach for the analysis of quantitative determination of drugs and their metabolism in biological samples. In this research work its applications was tested and reviewed under different sampling techniques. The basic concept of bioequivalence testing crossover design was used to make assessment of medicine for breast cancer methotrexate and tamoxifen. Effectiveness of methotrexate at initial stage was 2.38 and at advance stage it was 1.85 which means it was 43% effective at initial stage while 38% effective in advance stage. Effectiveness of tamoxifen at initial stage 3.19 at advance stage 3.68 which means it was 52% effective at initial stage while 57% effective in advance stage. The relation of bioequivalence testing and distance base inference was highlighted. An attempt was made to analyze the efficiency of both medicines at initial and advance stage of diagnostic of breast cancer.
Cited by 0
No indexed citations yet.
Related research
- Down-regulation of BMP8A, SMADs 1/5/8 and BAX Proteins Following Methotrexate-treatment in Testicular Tissue of Swiss Albino Mice — shares topic coverage
- Ginger and Honeybee Modulates MTX-induced Oxidative Stress in Kidney of Rats — shares topic coverage
- Effects of Ascorbic Acid, Dehydroascorbic Acid and Methotrexate on Breast Cancer Cell Viability — shares topic coverage
- Methotrexate Combination Effects with Genistein and Daidzein on MDA-MB-231 Breast Cancer Cell Viability — shares topic coverage
- Effect of Methotrexate and Tea Polyphenols on the Viability and Oxidative Stress in MDA-MB-231 Breast Cancer Cells — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.