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Research Article Open access CC BY 4.0

Heat Stress, Antioxidant Supplementation and HSP70 mRNA Expression in Growing Pigs

Arindam Chakraborty, Soumen Naskar, Simson Soren, Sanjib Borah, Donna Phangchopi, Snigdha Hazarika, Biju Borah, Sayed Nabil Abedin, Shiney George

Archives of Current Research International · pp. 152–163 · Published 4 Sep 2025

10.9734/acri/2025/v25i91484

Abstract

Heat stress poses significant challenges to livestock productivity, particularly in pigs, due to their limited thermoregulatory mechanisms. This study aimed to evaluate the seasonal effects of heat stress on growth performance, haematological and hormonal level, as well as the relative mRNA expression of HSP70 in growing pigs supplemented with melatonin and vitamin E. Results showed that haematological parameters, serum cortisol, lactate dehydrogenase, and average body weight were adversely affected during the summer season. While antioxidant supplementation did not significantly influence haematological profiles or LDH levels, it reduced cortisol levels during summer. Vitamin E supplementation resulted in a significant decrease in HSP70 mRNA expression during summer, indicating improved oxidative stability. Seasonal variations notably affect pigs' growth and health, with vitamin E supplementation reducing HSP70 expression during summer, highlighting the challenges of tropical climates.

Heat stress growing pigs antioxidants supplementation HSP70 expression

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