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Research Article Open access CC BY 4.0

Effect of Dexamathasone in Surgical Extraction of Mandibular Impacted Third Molar

Abdul Hayee Shaikh, Kashif Ali Channar, Ajeet Kumar, Naveed Iqbal, Junaid Shakeel, Uzma Shahid, Shumaila Shaikh, Nayel Syed, Aisha Jabeen, Mirza Tasawer Baig, Imran Qureshi

Journal of Pharmaceutical Research International · pp. 8–13 · Published 6 Feb 2021

10.9734/jpri/2020/v32i4731107

Abstract

Objective: The objective of this study was to determine the role of dexamethasone in mandibular third molar surgical extraction. Methodology: This cross sectional study was conducted in Oral & Maxillofacial surgery department, Liaquat University of Medical & Health sciences Hyderabad / Jamshoro. 50 cases were included in this study by using simple random sampling technique. All patients were divided into two groups. Patients in Group-A were given dexamethasone (DM)8 mg intramuscularly (IM) before surgery and 4 mg 24 hours after surgery and Augmentin tablet 625mg Q12 hrs. and Brufen 400 mg Q8 hrs. and patients in group-B were given Augmentin 625 mg BD and Brufen 400 mg  TDS post operatively only. The facial swelling was checked before and after surgery.All information was collected and entered in a proforma. Results: The study sample was consisted of 62% men and 38% women. Mean age was 26.9±6.64.The mean preoperative swelling was 109.20 ± 1.190 mm in control group and 109.44 ± 1.083 in DM group. After 48 hours of surgery, post extraction swelling increased in both group with mean swelling 114.28± 1.242 mm in control group and 114.64± 1.350 in DM group, after a week of surgery more swelling was reduced in DM group as compared to control group. Conclusion: It is found that Dexamethasone group showed decrease in swelling as compared to control group.

Dexamethasone impaction impactio corticosteroid and surgical extraction.

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