Facile Green Synthesis of Iron Oxide Nanoparticles Using Phoenix dactylifera L. Seed Extract and Their Antibacterial Applications
Abdul Majid, Farah Naz, Hatim Ali Jamro, Bilal Ansari, Sanaullah Abbasi, Sham Lal, Safdar Ali Ujjan
Journal of Pharmaceutical Research International · pp. 21–29 · Published 27 Apr 2021
10.9734/jpri/2021/v33i26B31478Abstract
Aim: The synthesis methods of iron oxide nanoparticles (IONPs) have got great attention in recent years, due to their variety in physicochemical properties and applications. This study aimed for the green synthesis of the IONPs using an aqueous extract of P. dactylifera L. seeds for its antibacterial applications. Methodology: IONPs were prepared in an aqueous seed extract of P. dactylifera L. The physicochemical characterisations were performed with transmission electron microscopy (TEM) to study the shape of obtained nanoparticle, energy-dispersive spectroscopy (EDS) for elemental confirmation of iron and oxygen, dynamic light scattering (DLS) for particles size measurement, vibrating sample magnetometer (VSM) for saturation magnetisation, Infrared spectroscopy (FTIR) for chemical confirmation of function groups and X-ray diffraction (XRD) for crystalline nature. The polyphenols contents were also determined; we suggest that the presence of phenolic compounds is the key element involved in the formation and the stabilisation of IONPs. Antibacterial activity was determined using disc diffusion assay and minimum inhibitory concentration (MIC) of the IONPs were determined by broth dilution assay. Results: The biosynthesised IONPs showed crystalline magnetite spherical morphologies with average diameter 30 nm. Discs with all the concentrations of IONPs tested in this study (10 - 100 ug.mL-1) showed antibacterial activity against bacterial strains tested (Staphylococcus epidermidis, Klebsiella pneumoniae and Pseudomonas aeruginosa). MIC values were found to be 30 ug.mL-1, 50 ug.mL-1 and 60 ug.mL-1 for S. epidermidis, K. pneumoniae and P. aeruginosa respectively. Conclusion: The biosynthesis of IONPs has provided, reliable, safe, simple and eco-friendly method. Hence, this study has focused on biological method of synthesis of IONPs. The IONPs synthesized in this study can be used as the therapeutic agents against bacteria.
Cited by 10
Manimehala U, Sneha Asha, Merin Tomy · Journal of Condensed Matter · 2025
Christian Nwabunwanne, Samson O. Aisida, Rabia Javed · Journal of the Indian Chemical Society · 2025
Hadia Shoaib, Ahmed Raza Sidhu, Umaima Ismail · Biogenic Wastes-Enabled Nanomaterial Synthesis · 2024
Muskan Bokolia, Deepanjali Baliyan, Ajay Kumar · International Journal of Environmental Analytical Chemistry · 2024
Abdallah Shanableh, Sourjya Bhattacharjee, Sefeera Sadik · Journal of Water Process Engineering · 2021
Raneev Thakur, Vimal Arora · International Journal of Polymeric Materials and Polymeric Biomaterials · 2022
Clément L. Inkoto, Laboratory of Natural Substances and Medicinal Chemistry, Department of Chemistry and Industry, Faculty of Science and Technology, University of Kinshasa, Democratic Republic of Congo, Dorothée D. Tshilanda · AIMS Materials Science · 2026
Miryam M. Luzala, Claude K. Muanga, Joseph Kyana · Nanomaterials · 2022
Mohamed Abdelmonem, Romesa Soomro, Norazalina Saad · Nano Biomedicine and Engineering · 2025
Mohamed Abdelmonem, Emmellie Laura Albert, Maha A. Alhadad · Precision Nanomedicine · 2024
Related research
- Characterization and Evaluation of the Antibacterial Activity of Silver Nanoparticles Synthesized by Green Method Using Phyllanthus emblica Leaf Extract — shares topic coverage
- Antibacterial and Phytochemical Activity of Gliricidia sepium against Poultry Pathogens — shares topic coverage
- Evaluation of Antibacterial Activity of Piper betel Leaves and Nigella sativa Seeds against Multidrug Resistant Food and Water Borne Pathogenic Bacteria: An in vitro Study Model — shares topic coverage
- Traditional and Molecular Identification of Bacterial Contamination from Honey (Processed and Unprocessed) and Their Control by Phytotherapy — shares topic coverage
- Antibacterial, Antioxidant Activity and Phytochemical Analysis of Euphorbia hirta Linn. — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
10
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.