Visceral Leishmaniasis Treatment and Its Challenges
Israt Jahan Khan Chowdhury, Md Fazlul Haque
South Asian Journal of Parasitology · pp. 307–322 · Published 1 Apr 2020
Abstract
Visceral leishmaniasis (VL) is generally termed as kala-azar, black fever, and Dumdum fever and it is known to be the most severe form of leishmaniasis. Without any proper diagnosis and treatment it causes high fatality rate. It is a disease generally caused by protozoan parasites of genus Leishmania. Miltefosine is the first oral treatment for this disease. The cure rate of miltefosine in Phase III clinical trials is 95%. This review is focused on the drugs available for the treatment of VL, their effectiveness and future challenges.
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