Skip to content
Research Article Open access CC BY 4.0

Formulation of Silver Nanoparticles from Grewia Asiatica Leaf Extract and their Biomedical Applications

Syed Bilal Hussain, Shabnam Iqbal, Sadaf Noor, Muhammad Zubair

Asian Journal of Biochemistry, Genetics and Molecular Biology · pp. 45–55 · Published 18 Oct 2023

10.9734/ajbgmb/2023/v15i3338

Abstract

Nanotechnology is a well-advanced area and several types of nanoparticles have been synthesized. Different types of nanoparticles have been synthesized so far using different techniques. It is most practical to produce nanoparticles from plant extracts for use in medicine and other applications. In this study, silver nanoparticles were synthesized by Grewia asiatica leaf extract. Synthesized nanoparticles were characterized by different techniques including Ultraviolet-visible (UV) spectroscopy, X-ray diffraction (XRD), Dynamic light scattering (DLS), and Scanning electron microscopy (SEM). Results showed a characteristic peak of silver nanoparticles in UV-region at 425nm, while DLS analysis revealed the z-average size of synthesized particles i.e., 461.6nm and -28.4mV zeta potential. SEM analysis revealed the amorphous surface morphology. The antibacterial and antioxidant activity of silver nanoparticles were also evaluated. Silver nanoparticles showed significant antibacterial activity against both gram-positive and gram-negative bacteria. A maximum zone of inhibition of 16mm diameter was observed against Bacillus subtilis and Klebsiella pneumonia. While results of antioxidant activity showed a 43.27μg/ml IC50 value. In conclusion, Grewia asiatica leaf extract is a good source to synthesize silver nanoparticles. Also, green synthesized silver nanoparticles could act as potential antibacterial and antioxidant agents.

Nanotechnology biomedical application Grewia sp extract

References (23)

  1. 1 Completely “Green” Synthesis and Stabilization of Metal Nanoparticles [DOI]
  2. 2 Synthesis of silver nanoparticles: chemical, physical and biological methods.
  3. 3 Green synthesis, biomedical and biotechnological applications of carbon and graphene quantum dots. A review [DOI]
  4. 4 Solventless synthesis and optical properties of Au and Ag nanoparticles using Camellia sinensis extract [DOI]
  5. 5 Biogenesis of metal nanoparticles and their pharmacological applications: present status and application prospects [DOI]
  6. 6 Green synthesized silver nanoparticles: Optimization, characterization, antimicrobial activity, and cytotoxicity study by hemolysis assay [DOI]
  7. 7 Green synthesis of silver nanoparticles and their applications as an alternative antibacterial and antioxidant agents [DOI]
  8. 8 Nanobiotechnology perspectives. Role of nanotechnology in the food industry: a review [DOI]
  9. 9 Microwave Accelerated Green Synthesis of Stable Silver Nanoparticles with Eucalyptus globulus Leaf Extract and Their Antibacterial and Antibiofilm Activity on Clinical Isolates [DOI]
  10. 10 Antibacterial activity of silver nanoparticles (biosynthesis): A short review on recent advances [DOI]
  11. 11 Anti-diabetic Potential of Silver Nanoparticles Synthesized with Argyreia nervosa Leaf Extract High Synergistic Antibacterial Activity with Standard Antibiotics Against Foodborne Bacteria [DOI]
  12. 12 Green synthesis of silver nanoparticles from leaf extract Azhadirachta indica and to study its anti-bacterial and antioxidant property
  13. 13 Biosynthesis, Optimization and Characterization of Silver Nanoparticles Using a Soil Isolate of Bacillus pseudomycoides MT32 and their Antifungal Activity Against some Pathogenic Fungi [DOI]
  14. 14 Recent Advances in the Gastrointestinal Fate of Organic and Inorganic Nanoparticles in Foods [DOI]
  15. 15 Efficient photocatalytic degradation of industrial wastewater dye by Grewia asiatica mediated zinc oxide nanoparticles [DOI]
  16. 16 Recent progress in determination of ochratoxin a in foods by chromatographic and mass spectrometry methods [DOI]
  17. 17 Green route synthesis of metallic nanoparticles using various herbal extracts: A review [DOI]
  18. 18 Synthesis of Fluorescent Silver Nanoclusters: Introducing Bottom-Up and Top-Down Approaches to Nanochemistry in a Single Laboratory Class [DOI]
  19. 19 Traditional uses, phytochemistry, quality control and biological activities of genus Grewia [DOI]
  20. 20 Synthesis and enhanced antibacterial using plant extracts with silver nanoparticles: Therapeutic application [DOI]
  21. 21 Identification of bioactive compounds from the ethnomedicinal plant Senna alata (L.) Roxb. (fabaceae) through in vitro and molecular docking analysis against ?-glucosidase enzyme: a diabetic drug target [DOI]
  22. 22 Effect of habitat loss and anthropogenic activities on butterflies survival: A review
  23. 23 Synthesis and Characterization of Nanoparticles Used in Consumer Products [DOI]

Cited by 0

No indexed citations yet.

Article metrics

Real usage data collected on this platform.

43

Page views

0

PDF downloads

20

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.