The Prevalence of Prediabetes and Its Association with Metabolic Syndrome and Insulin Resistance in the Central Indian Population

Abstract

Pre-diabetes can be recognized as either impaired fasting glucose (IFG) or impaired glucose tolerance (IGT). One hundred forty subjects participating in the different medical hospital out patient’s department (OPDs) were selected. The study comprised sixty control and sixty prediabetic individuals aged 30-60 years. A positive correlation was observed between fasting serum glucose, anthropometric parameters cardiovascular parameters and biochemical parameters except for HDL cholesterol which showed a negative correlation. This study has important implications for identification of subjects at higher risk for future type-2 diabetes and suggested that mass screening of aggressive risk modification and close follow-up should be considered for prediabetic subjects with metabolic syndrome. Appropriate intercession in the form of weight reduction, changes in dietary habits and increased physical activity could help to prevent, or at least delay the onset of diabetes and thus reduce the burden due to noncommunicable diseases in India.