P-Wave Variation and Effective Hemodialysis in Chronic Hemodialysis Patients

Abstract

Background: Analyzing a 12‐lead surface electrocardiogram (ECG), specifically variability of the P wave interval, we aimed to assess whether or not P-wave variation can be used as a good indicator of effective hemodialysis with chronic hemodialysis patients. Methods:  Data from 56 patients receiving HD over a period of one year were collected; the same group of patients was then evaluated during treatment with conventional HD. Electrolyte values were obtained, and Holter ECGs were performed. Results:  P maximum was 108±76 ms at the beginning and showed a decrease by the end of dialysis to 101±37ms (P<0.0001). Although statistically significant decreases were observed in potassium and a significant increase in natremia and calcium levels after hemodialysis, no such changes were observed in other blood electrolytes. Conclusion: The decrease of P-wave after hemodialysis and its significant correlation with the variability of natremia, calcemic and potassium serum level, which can be used as an indicator of effective hemodialysis.