Giant Multiloculated Ameloblastoma Causing Extensive Destruction of the Mandible and Midface: A Case Report

Abstract

Ameloblastoma is a slow-growing odontogenic tumor that can cause painless swelling of the face. The local aggressive behavior of the tumor may directly damage surrounding soft and hard tissues. The study aims to report a rare case of a giant multiloculated ameloblastoma with extensive mandibular and midfacial destruction and to highlight its diagnostic and surgical management challenges. Herein we present a rare case of giant ameloblastoma in a male patient with massive enlargement of the left side of the face, resorption of hemi-mandible and left maxilla, and destruction of facial skeleton. Treatment consisted of radical hemimandibulectomy for removal of the tumorous mass, with stabilization using a reconstruction plate. For giant ameloblastoma, the diagnosis and treatment strategies for each surgical intervention depend on an accurate understanding of anatomical structures, including their positions and spatial relationships. CT imaging facilitates precise identification of the lesion's extent and location, providing additional critical information that can assist in the selection of suitable treatment options. In summary, despite the stability of human anatomy over time, accurate understanding of anatomical structures and their clinical manifestations remains essential for effective diagnosis and formulation of treatment strategies in contemporary surgical practices.