Novel Scientific Appraisal of Elaeocarpus ganitrus the Rudraksha: Nano Silver Synthesis with Aspects of Variation in Concentration Antimicrobial Activity and In vitro Biocompatibility

Abstract

Aims: The remarkable non-degradable distinctive feature of the Rudraksha bead renders reutilization of its resources and inexhaustibility of its potentiality to mediate innumerable silver nanoparticle syntheses. The present study is a step forward towards high prospects of manoeuvred nano silver manufactured for many essential applications. Study Design: In this nanoregime we bring forth a glorious green route for flabbergasting silver nanoparticle fabrication, with the intervention of the five faced seed of the plant Elaeocarpus ganitrus Roxb, the Rudraksha bead. Aspects, of the variation in concentration of the precursor as well as the mediator on the physico-chemical nature of the silver nanostructure, its antimicrobial activity, together with the issues of its biocompatibility, have been dealt here. Place and Duration of Study: Chemistry Department and Biotechnology Department, Motilal Nehru National Institute of Technology, India, between April 2011 and August 2012. Methodology: The Rudraksha extracts were prepared and biosyntheses of silver nanoparticles were conducted and different parameters were studied together with various characterization. Results: The silver nanoparticles produced are chiefly spherical with variable size. There exists also variation in size and silver content depending upon the concentration of precursor and mediator. The antimicrobial activity of the nano silver produced is high with good biocompatibility. Conclusion: The inexhaustible characteristic of the non-degradable Rudraksha facilitates incessant biocompatible nano silver production.