Health-related Quality of Life Predictors in Children and Adolescents with Sickle Cell Disease: A Systematic Review
Adedokun O. Ojelabi, Yitka Graham, Jonathan Ling
International Journal of TROPICAL DISEASE & Health · pp. 1–14 · Published 4 Mar 2017
10.9734/IJTDH/2017/31954Abstract
Aim: The aim of this systematic review is to examine the predictors of HRQL(health-related quality of life) in children and adolescents (aged 18 years and under) with SCD(Sickle Cell Disease). Methodology: A systematic review was conducted to identify published articles meeting defined inclusion criteria to identify determinants of HRQL in children and adolescents with SCD. Results: Children and adolescents with SCD have poor HRQL compared with healthy peers, normative populations or siblings. A number of socio-demographic variables, socioeconomic markers and psychosocial factors along with clinical measures predict HRQL in the study population. These include child demographics, family income, parental support, depression, comorbidities and frequency of hospitalisation. Conclusion: In managing SCD in children and adolescents, healthcare providers should pay attention to psychosocial variables along with clinical measures. This holistic approach to disease management may help to mitigate the adverse impact of the disease on people with SCD.
Cited by 14
Anna M. Hood, Lori E. Crosby, Eva Hanson · Ethnicity & Health · 2020
Akshat Jain, Lisa Roberts, Safiye Sahin · Journal of Sickle Cell Disease · 2025
Luís Eduardo Batista, Marcia Pereira Alves dos Santos, Marly Marques da Cruz · Ciência & Saúde Coletiva · 2022
Adedokun Oluwafemi Ojelabi, Afolabi Elijah Bamgboye, Jonathan Ling · PLOS ONE · 2019
Suthan Pandarakutty, Judie Arulappan · Applied Nursing Research · 2024
Anna M. Hood, Emily A. McTate, Naomi E. Joffe · Issues in Clinical Child Psychology · 2020
Mehrnaz Ahmadi, Samira Beiranvand, Saeed Poormansouri · Annals of Hematology · 2022
Luís Eduardo Batista, Marcia Pereira Alves dos Santos, Marly Marques da Cruz · Ciência & Saúde Coletiva · 2022
Anna M. Hood, Charles T. Quinn, Christopher D. King · Complementary Therapies in Medicine · 2020
Vera Lúcia Duarte da Costa Mendes, Patrícia A. Risso, Marcia Pereira Alves dos Santos · Ciência & Saúde Coletiva · 2024
Showing 12 of 14 known citations — external sources report more than can currently be individually listed.
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