Post-Artesunate Late Haemolytic Anemia in a  17-Month-Old Infant Followed for Severe Malaria at the Yalosase Health Center, Isangi, DR Congo

Dieudonné Lobela Bumba; Issa Yakusu Issa; Ossinga Bassandja; Mankulu N’Sila; Beatrice Lisimo; Bruce Wembolua Shinga; Kendewa sabiti; Bokanga Ekelenge; Francy Baelongandi Folo; Atoba Bokele

Research Article Open access CC BY 4.0

Post-Artesunate Late Haemolytic Anemia in a 17-Month-Old Infant Followed for Severe Malaria at the Yalosase Health Center, Isangi, DR Congo

Dieudonné Lobela Bumba, Issa Yakusu Issa, Ossinga Bassandja, Mankulu N’Sila, Beatrice Lisimo, Bruce Wembolua Shinga, Kendewa sabiti, Bokanga Ekelenge, Francy Baelongandi Folo, Atoba Bokele

Asian Journal of Case Reports in Medicine and Health · pp. 200–203 · Published 28 Dec 2021

Abstract

Artesunate is an artemisinin derivative with rapid and potent parasiticidal power. However, cases of delayed hemolytic anemia described in the literature can be fatal, especially in children. We report a rare case of late hemolytic anemia in an infant. This was a 17 month old infant with a history of severe malaria treated with artesunate two weeks ago, seen in consultation for hemolytic anemia with negative GE. Both HBsAg and anti-HCV serology were negative. Considering the context, the diagnosis of post-artesunate late hemolytic anemia was retained and the patient had progressed well after transfusion.

Late hemolytic anemia severe malaria artesunate injection Isangi

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Dieudonné Lobela Bumba, Issa Yakusu Issa, Ossinga Bassandja, Mankulu N’Sila, Beatrice Lisimo, Bruce Wembolua Shinga, Kendewa sabiti, Bokanga Ekelenge, Francy Baelongandi Folo, Atoba Bokele (2021). Post-Artesunate Late Haemolytic Anemia in a 17-Month-Old Infant Followed for Severe Malaria at the Yalosase Health Center, Isangi, DR Congo. Asian Journal of Case Reports in Medicine and Health , 200–203.

Affiliations

Dieudonné Lobela Bumba — Infectious and Tropical Diseases Department, National University Hospital of Fann, Dakar, Senegal and Higher Institute of Medical Techniques of Yangambi, DR Congo.
Issa Yakusu Issa — Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.
Ossinga Bassandja — Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.
Mankulu N’Sila — University of Cepromad, Faculty of Public Health and Medicine of Proximity, Kisangani, DR Congo.
Beatrice Lisimo — Cinquantenaire Hospital of Kisangani, Kisangani, DR Congo.
Bruce Wembolua Shinga — Infectious and Tropical Diseases Department, National University Hospital of Fann, Dakar, Senegal.
Kendewa sabiti — Higher Institute of Medical Techniques of Yangambi, DR Congo.
Bokanga Ekelenge — Department of Gynecology-Obstetric, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.
Francy Baelongandi Folo — Provincial Health Division, Tshopo, DR Congo.
Atoba Bokele — Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, DR Congo.

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