Skip to content
Research Article Open access CC BY 4.0

Isolated Unilateral Temporal Coloboma of the Lens

Suwarna Suman, Arushi Kumar, Hemant Uttamrao Rathod

Ophthalmology Research: An International Journal · pp. 1–6 · Published 3 Jan 2024

10.9734/or/2024/v19i1408

Abstract

Lens coloboma is a rare congenital anomaly that occurs due to failure of the foetal fissure to close completely causing an incomplete formation of the lens, so usually inferonasal. Temporal lens coloboma is extremely rare; reported cases were associated with ocular or systemic anomalies. We report a rare case of unilateral atypical temporal lens coloboma without any iris abnormality and posterior segment coloboma or any other ocular or systemic anomaly. An 18-year-old female presented with a gradually progressive painless diminution of vision in her left eye for two years. There was no history of trauma, and family history was non-contributory. The systemic examination was normal. Ocular examination revealed a vision of 6/6 in the right eye and 6/60 in the left eye improving to 6/24 with pinhole and unilateral atypical temporal coloboma of the crystalline lens in the left eye after dilatation. The rest of the anterior segment and fundus examination was normal. No abnormality was detected in the right eye. The best corrected visual acuity of 6/6 OD and 6/9 OS was achieved with spectacle correction at 6 months of follow-up. This case is a rare presentation of unilateral atypical coloboma located temporally without any iris abnormality and posterior segment coloboma or any other ocular or systemic anomaly. Early correction of refractive error and astigmatism results in good prognosis.

Lens coloboma atypical coloboma temporal coloboma embryonic fissure zonules

References (18)

  1. 1 Specification of the vertebrate eye by a network of eye field transcription factors [DOI]
  2. 2 Ocular coloboma: a reassessment in the age of molecular neuroscience [DOI]
  3. 3 Ocular Anatomy Embryology and Teratology [DOI]
  4. 4 Ocular anatomy, embryology, and teratology
  5. 5 Morphogenetic defects underlie Superior Coloboma, a newly identified closure disorder of the dorsal eye [DOI]
  6. 6 Congenital lens coloboma and associated pathologies [DOI]
  7. 7 Environmental risk factors in congenital malformations of the eye [DOI]
  8. 8 Eye birth defects in humans may be caused by a recessively-inherited genetic predisposition to the effects of maternal vitamin A deficiency during pregnancy.
  9. 9 Molecular regulators involved in vertebrate eye development [DOI]
  10. 10 Developmental Giant Retinal Tears Associated With Lens Coloboma [DOI]
  11. 11 The Genesis of Atypical Ocular Coloboma [DOI]
  12. 12 Lens coloboma treated with lens surgery [DOI]
  13. 13 Lens coloboma and associated ocular malformations. [DOI]
  14. 14 Atypical Coloboma of the Iris and Choroid [DOI]
  15. 15 Coloboma of the lens, optic nerve hypoplasia, and orbital hemangioma – A possible developmental field defect [DOI]
  16. 16 Lens Coloboma and Alport-Like Glomerulonephritis [DOI]
  17. 17 Progressive lenticular astigmatism associated with nuclear sclerosis and coloboma of the iris, lens, and choroid: case report.
  18. 18 Concerning Congenital Coloboma of the Lens [DOI]

Cited by 0

No indexed citations yet.

Article metrics

Real usage data collected on this platform.

38

Page views

0

PDF downloads

12

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.