Reproductive Toxicity & Biomarker Response of Male Albino Rats (Rattus norvegicus) to a Daily Dose of Beer
Obemeata E. Oriakpono, Lebura K. Sam-Bariepie
Asian Food Science Journal · pp. 1–7 · Published 6 Nov 2018
10.9734/AFSJ/2018/40705Abstract
The effect of Beer was evaluated on Albino rats. Sperm count, kidney function test, liver test, red blood cell, pack cell volume, haemoglobin, white blood cell, platelets, lymphocytes were evaluated. The results revealed the mean serum Na, K and Cl reduced from 155.33, 6.13 and 99.33 in week 1 to 146.33, 4.80 and 87.3 in week 4 with a significant difference (P<0.05) across the group when compared to the average control for Na and K. HCO3 had a mean of 19.0 in week 1 and a mean of 21 in week 4 in the treated group and the control group had 23.33 in week 1 and 24.33 in week 3. AST had a mean of 47.33 in week 1 which reduced to 23.33 in week 4 while ALT had a mean of 14.00 in week 1 and 15.00 in week 4 with a significant difference (P<0.05) across the group. The mean serum protein had a mean of 61.77 in week 1 and a mean of 68.11 in week 4 but the treated group was generally lower than the control group. Mean PCV reduced from 33.33 in week 1 to 25.13 in week 4, Hb from 11.20 in week 1 to 12.60 in week 3 then up to 13.35 in week 4 with a significant difference (P<0.05) when comparing the test with the average control, WBC had a mean of 8.60 in week 1 and 9.03 in week 4 in the treated group, Platelet count was 300 in week 1 and 514 in week 4 with significant difference (P<0.05) when compared to the average control. RBC had a mean of 5.0 in week 1 and 7.23 in week 4. Lymphocyte for week 1 had a mean value of 65 and decreased to 62.60 in week 4 with a significant difference (P<0.05) when compared to the average control. While the mean sperm count was 62.60, 115 and 125 in week 1, 2 and 3 with the control group having 84, 475 and 575 in week 1, 2 and 3 respectively. This showed that Beer had a negative effect with a significant difference (P<0.05) on the sperm count in the test when compared with the control. These findings demonstrate that Beer had a detrimental effect on the sperm count, liver kidney and on the haematological parameter.
Cited by 0
No indexed citations yet.
Related research
- Smoking Effects of Marijuana and Cigarette on Blood Chemistry, Hematology and Plasma Dopamine Levels in Young Adults — shares topic coverage
- Effects of Hydro-ethanolic Leaf Extract of Tithonia diversifolia on Parasitaemia Level, Serum Metabolites and Histopathology of Organs in Swiss Albino Mice Infected with Plasmodium berghei NK65 — shares topic coverage
- Common Findings in Ultrasound Examination of the Liver and Kidney in Sokoto Metropolis — shares topic coverage
- Liver Profile of Artemether-lumefantrine-tinidazole in Healthy and Parasitized Mice — shares topic coverage
- Sonographic Assessment of Maternal Portal Vein Diameter in Healthy Pregnancy in South-South Nigeria — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.