Knowledge, Attitude and Acceptance of Autologous Stem Cell Transplantation amongst Patients with Multiple Myeloma in Nigeria
Emmanuel Wobo, Ifechukwude Anita Osunde, Adaeze Onyinyechi Okwu, Linda Anucha Dublin-Green, Chinyere Eunice Eze, Akpevwe Deborah Maduka, Opadeyi Oluseyi Michael, Okwummuo Emeka Paul, Otumu Odianosen Sunday, Oji Anya Nnachi, Eniefiok Hezekiah Jumbo
International Journal of Research and Reports in Hematology · pp. 95–103 · Published 19 Feb 2026
10.9734/ijr2h/2026/v9i1213Abstract
Background: The treatment of newly diagnosed Multiple Myeloma continues to evolve rapidly. Autologous stem cell transplantation remains the backbone in the management of the MM even in the era of novel agents. This procedure is not readily available in Nigeria AIM; To assess the level of knowledge, attitude and acceptance of ASCT in management of multiple myeloma. Materials and Methods: This multicenter cross-sectional study was conducted in 9 tertiary hospitals in Nigeria from 1st of March 2025 – 31st December 2025. A pretested structured questionnaire was administered to respondents. Respondents were adult patients diagnosed with multiple myeloma Results: 36 patients diagnosed with multiple myeloma were included in this study. Nineteen (52.8%) were males were 17(47.2%) were females. Twenty-one (58.3%) responders have heard of ASCT in multiple myeloma while 15 (41.7%) have not heard of ASCT. Twenty-three (63.9%) respondents agreed that ASCT can be done successfully in Nigeria while 13 responders (36.1%) did not agree. Majority of those that did not agree, cited lack of equipment as a major barrier. Twenty-seven (75%) patients agreed that the cost of the procedure can be a major drawback in carrying out the procedure in Nigeria. Twenty-five (69.4%) identified the perceived side effects or complication of the procedure as major road block to accessing the procedure. the overall acceptance of ASCT amongst Multiple myeloma patients was 52.8% Conclusion: The Awareness of ASCT in multiple myeloma in Nigeria is high but relatively low when compared with reports from developed countries. Majority of the respondents agreed that ASCT can be done successfully in Nigeria with an acceptance rate of (52.8%) However, access barriers such as lack of relevant equipment, lack of expertise, fear of complications and high cost of procedure must be addressed so that more Nigerians can embrace this beneficial procedure.
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