The Aicardi Syndrome: Case Report about a 3-month-old Infant

Abstract

Aicardi syndrome, exclusively occurring female patient, was originally characterized by triad: agenesis of the corpus callosum, distinctive chorioretinal lacunae, and infantile spasms. Besides the triad, several other findings are present in patients with this condition. We here shortly report the case of a 3-month-old female infant with Aicardi syndrome, who had non-consanguineous parents. Triad was seen: infantile spasm with abnormal EEG, agenesis of corpus callosum revealed by MRI, and chorioretinal lacunae of the posterior pole. We diagnosed this condition as Aicardi syndrome. After treatment with vigabatrin and psychomotor sessions at the age of 3 months, it is noted that the attacks were reduced and psychomotor development was normal at the age of 5 months. We summarized the clinical characteristics of this syndrome based on the literature survey.