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Research Article Open access CC BY 4.0

Phenyl Hydrazone Derivatives of Benzofuran: Synthesis and Their Antimicrobial Activities

Sadath Ali, Abhishek Raj Pachori, Mohamad Taleuzzaman, Chandrakala ., Sadaf Jamal Gilani

Asian Journal of Chemical Sciences · pp. 1–7 · Published 29 Jun 2017

10.9734/AJOCS/2017/34772

Abstract

A series of (Z)-1-benzo [b] furan-2-yl-3-(substituted phenyl) prop-2-en-1-one 1-phenylhydrazone derivatives (C1-C12) of benzofuran were synthesized with satisfactory yield and pharmacologically evaluated for their in vitro antimicrobial activity. All the synthesized compounds were in good agreement with elemental and spectral data. A majority of the tested compounds showed good to moderate antimicrobial activity against all tested pathogenic bacterial and fungal strains.

Benzofuran phenylhydrazone antimicrobial activity

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