Malignant Transformation of Radicular Cyst/Residual Cyst: A Review of Literature
Bassel Tarakji, Ayesha Shireen, Ayesha Umair, Saleh Nasser Azzeghaiby, Ibrahim Alzoghaibi, Salah Hanouneh
Journal of Advances in Medicine and Medical Research · pp. 4278–4288 · Published 5 Jun 2014
10.9734/BJMMR/2014/9536Abstract
Aim: The aim of this study is to review the literature concerning malignant transformation of radicular cyst. Material and Method: A literature search using MEDLINE, accessed via the National Library of Medicine PubMed interface (http://www.ncbi.nlm.nih.gov/pubmed), searching for articles relating to the malignant transformation of radicular/residual cyst written in English from 1960-2013. Results: Our search identified only fourteen studies available to date in English written literature. No randomized controlled trials to assess the possibility of malignant transformation of radicular/residual cyst were in the literature. Conclusion: The development of malignancy from radicular /residual cysts is rare, however, it should always be considered as a differential diagnosis. The numbers of studied cases in literature are few but small number of case series & case reports are available. Also it is recommended that further work involving large series of tumors arising from radicular /residual cyst to determine the malignancy potential.
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