Metoprolol-induced Psoriasiform Drug Eruption: A Case Report

Abstract

Aim: We report the case of drug-induced psoriasiform eruptions in a middle aged known hypertensive and diabetic woman being treated for paroxysmal cardiac arrhythmias with metoprolol. Case Presentation: A 58-year-old known hypertensive and diabetic woman with supraventricular tachycardia presented with itchy rashes in between the breast and weakness a day after switching propranolol for metoprolol succinate (Betaloc Zok) because of inadequate response. On physical examination, thick, and scaly erythematous papules of various sizes were found in between the breast. Routine laboratory test results were within normal limits. Metoprolol succinate was withdrawn, and improved on topical corticosteroids (1% hydrocortisone). Discussion: The features of the case reported above are believed to be those of drug induced psoriasis because the lesions disappeared following the discontinuation of the drug. Conclusion: We present a case of metoprolol induced psoriasiform eruption in a Nigerian woman. There was no cross-reactivity when other members of the class were prescribed for her.