Michelia champaca L. Derived Phytochemicals against Peptidase Do of Bordetella pertussis Causing Cough
Sanjeeb Kumar Dash, Sidhartha Ray, Smruti Ranjan Behera, Soumya Jal, Dipankar Bhattacharyay
Journal of Pharmaceutical Research International · pp. 133–135 · Published 3 Jun 2020
10.9734/jpri/2020/v32i830533Abstract
Phytochemicals from Michelia champaca L. plant extract are traditionally used to cure cough. Cough can be caused by many reasons. Caugh can be caused by the infection of Bordetella pertussis. The objective of the study is to identify the phytochemical of Michelia champaca capable of curing cough. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that magnoflorine can effectively deactivate the peptidase Do enzyme which will interrupt the life cycle of the microorganism and inhibit the multiplication.
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