Molecular Evaluation of COVID-19 in Pandemic Era

Abstract

COVID-19 (SARS-CoV-2) has recently emerged as an ongoing pandemic disease or probably syndemic and became the latest threat to global health. The main route of transmission of virus droplet start with respiratory problems coughing, sneezing, fever during infection period, which may end up with death, if not treated. Many emerging epidemiological factors have made COVID-19 as global alarming disease. To control the outbreak of COVID-19, a critical management along with quarantine measure is applicable, which requires early detection of infection. The early detection of COVID-19 infection is playing a vital role in controlling of progression of illness and limiting viral spread within the population. Therefore, reliable, highly specific and sensitive diagnosis techniques are necessary for its early detection.  Among several detection techniques, qRT-PCR is the rapidly employed, sensitive and widely accepted technique. In present review, different molecular techniques with emphasis on qRT-PCR for early diagnosis of emerging COVID-19 will be discussed.