Moringa oleifera Derived Phytochemicals against  2-hydroxy-3-oxopropionate Reductase of  Salmonella typhi Causing Typhoid

Sonali Suchismita Behera; Seema Suvadarshini; Ipsita Aparajita Mohapatra; Sonali Dash; Akshaya Kumar Sahoo; Soumyashree Nayak; Meenakshee Mohanty; Punya Prateek Majhi; Srimay Pradhan

doi:10.9734/jpri/2020/v32i930534

Research Article Open access CC BY 4.0

Moringa oleifera Derived Phytochemicals against 2-hydroxy-3-oxopropionate Reductase of Salmonella typhi Causing Typhoid

Sonali Suchismita Behera, Seema Suvadarshini, Ipsita Aparajita Mohapatra, Sonali Dash, Akshaya Kumar Sahoo, Soumyashree Nayak, Meenakshee Mohanty, Punya Prateek Majhi, Srimay Pradhan

Journal of Pharmaceutical Research International · pp. 94–97 · Published 20 Jun 2020

10.9734/jpri/2020/v32i930534

Abstract

Phytochemicals from Moringa oleifera plant extract can cure Typhoid. It is caused by Salmonella typhi. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 4,8,12,16-tetramethylheptadecan-4-olide can effectively deactivate the 2-hydroxy-3-oxopropionate reductase enzyme thereby interrupting the life cycle of the organism.

Phytochemical Moringa oleifera Salmonella typhi typhoid.

Cited by 1

Harnessing medicinal plants: New hope for typhoid fever antibacterial agents - Mini review

Ifeoluwa Margaret Idowu, Tian-Xiang Li, E. A. Orgah · Natural Therapy Advances · 2025

Ameliorative Potentials of Yoyo Bitters and Aqueous Leaf Extract of Moringa oleifera in Arsenite Induced Inflammatory Dysfunctions in Male Wistar Rats — shares topic coverage
Morphological and Biochemical Effects of Aqueous Extract of Moringa oleifera Leaf on Cobalt Chloride-Induced Cerebral Damage in Adult Wistar Rats — shares topic coverage
Antimicrobial Activity of Moringa oleifera Leaf against Isolates of Beef Offal — shares topic coverage
Phytochemical Profiling and Anti-MRSA Activity of Extracts from Moringa oleifera Lam. and Senna occidentalis (L.) Link Cultivated under Organic Conditions — shares topic coverage
Influence of Moringa oleiferea Seed Meal and Yam Blend in Body Weight and Glucose Level of Alloxan Induced Diabetes Mellitus Male Albino Rats — shares topic coverage

Access this article

View at publisher

Cite this article

Sonali Suchismita Behera, Seema Suvadarshini, Ipsita Aparajita Mohapatra, Sonali Dash, Akshaya Kumar Sahoo, Soumyashree Nayak, Meenakshee Mohanty, Punya Prateek Majhi, Srimay Pradhan (2020). Moringa oleifera Derived Phytochemicals against 2-hydroxy-3-oxopropionate Reductase of Salmonella typhi Causing Typhoid. Journal of Pharmaceutical Research International , 94–97. https://doi.org/10.9734/jpri/2020/v32i930534

Affiliations

Sonali Suchismita Behera — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Seema Suvadarshini — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Ipsita Aparajita Mohapatra — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Sonali Dash — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Akshaya Kumar Sahoo — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Soumyashree Nayak — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Meenakshee Mohanty — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Punya Prateek Majhi — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Srimay Pradhan — School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.

Metrics

0
Views: 0
Downloads: 1
Citations: 0
Outbound

Full metrics

Article metrics

Real usage data collected on this platform.

0

Page views

0

PDF downloads

0

Outbound clicks

1

Citations

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

No views recorded yet.

Traffic sources

Referring site, by host.

No traffic recorded yet.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.