Multiorgan Failure Associated with Epstein-Barr Viremia-An Elusive Diagnosis: A Case Series
Arun Agarwal, Mudit Agarwal, Anudeep Saxena, Sheel Bhadra Jain
International Journal of TROPICAL DISEASE & Health · pp. 1–8 · Published 21 Feb 2018
10.9734/IJTDH/2018/39649Abstract
Fulminant Epstein Barr Virus (EBV), also known as (herpes simplex virus-4(HSV-4) induced multiple organ failure is rarely reported and should be considered a potential diagnosis in patients with multiple organ failure. From a clinical perspective, it should be remembered that fulminant herpes simplex Virus (HSV) infection may masquerade as “routine” bacterial severe sepsis/septic shock. This potentially fatal condition should be diagnosed early and treated. Here we describe three cases who were admitted with multi organ dysfunction and two of them finally deceasing in a septic shock with multi organ failure. No bacterial or fungal infection could be detected in one of these cases and were adequately treated in other two cases. The presence of EBV (HSV-4) was detected in plasma confirming EBV viremia. The presentation, clinical course and management are discussed.
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