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Research Article Open access CC BY 4.0

N-acetylcysteine in Psychiatric Disorders: Possible Role of Cysteinet Deregulation

Marcos Arturo Martínez-Banaclocha

International Neuropsychiatric Disease Journal · pp. 1–6 · Published 15 Oct 2018

10.9734/INDJ/2018/44483

Abstract

In the last years, several clinical studies have shown the usefulness of N-acetylcysteine (NAC) in psychiatric diseases including a role in some drug abuse disorders. Although the glutathione replenishment and the antioxidant activity of NAC have been suggested as the principal mechanisms to improve such a wide range of conditions, these actions seem to be unspecific and insufficient to explain all reported effects. The present paper proposes that cysteinet (cysteine network) may be deregulated in psychiatric diseases explaining the wide-range beneficial actions of NAC supplementation.  

N-acetylcysteine cysteine psychiatric diseases psychosis diabetes cysteinet

Cited by 4

N-acetyl-cysteine in Schizophrenia: Potential Role on the Sensitive Cysteine Proteome

Marcos Martínez-Banaclocha · Current Medicinal Chemistry · 2020

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