Microwave Supported Solvent Free Reaction of EMME in the Synthesis of Pyrazolopyrimidopyrimidines
D. Shah Rina, M. Shah Nirmal, C. Ramani Vivek
Asian Journal of Applied Chemistry Research · pp. 1–9 · Published 24 Apr 2018
10.9734/ajacr/2018/v1i19602Abstract
Diethyl ethoxy-methylenemalonate the versatile reagent used to synthesize pyrazolopyrimidopyrimidines (3) as antimicrobial agents from the reaction between EMME and 1-substituted 3-(methylthio) 3H-pyrazolo [3,4-d]pyrimidine-4-amines (1) using Gould Jacob reaction. A comparison of conventional and microwave supported solvent-free reaction has been studied.
Cited by 1
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