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Research Article Open access CC BY 4.0

Biological Properties and Phytochemical Analysis of Fractions and Total Extracts of Cylicodiscus gabunensis Harms and Morinda lucida Benth

Cédric Sima Obiang, Rick Léonid Ngoua Meye Misso, Elvis Otogo N’Nang, Joseph Privat Ondo, Guy Roger Ndong Atome, Louis Clément Obame Engonga, Edouard Nsi Emvo

Journal of Advances in Microbiology · pp. 29–39 · Published 19 Mar 2021

10.9734/jamb/2021/v21i230325

Abstract

Two plants used in traditional medicine from Gabon were studied. The aim of this study was to study the biological properties and phytochemical analysis of Cylicodiscus gabunensis Harms and Morinda lucida Benth. These extracts were subjected to antimicrobial (diffusion, dilution), antioxidant (DPPH, ABTS) and inhibition of protein denaturation. The water-ethanol, water-acetone extracts and the partitioned extracts (F1 and F2) of Cylicodiscus gabunensis showed the greatest antibacterial activity on the majority of microbial strains and a good inhibition of denaturation with IC50 of 58.75 ± 2.10; 19.16 ± 2.00; 69.50 ± 2.00 and 17.49 ± 1.20 μg / mL respectively, compared to standards. Similarly, these extracts of Cylicodiscus gabunensis have anti-free radical capacities close to standards including vitamin C and butylated hydroxyanisole. The phytochemicals present in the extracts of Cylicodiscus gabunensis and Morinda lucida may be responsible for the biological activities studied.

Antibacterial denaturation inhibition anti-free radical DPPH ABTS

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