Bridging Polycystic Ovarian Syndrome and Periodontitis: A Review of Oral-systemic Health Interactions
Suganthi R, R. Saravana Kumar, Pratebha B, Narayane R
Asian Journal of Dental Sciences · pp. 186–199 · Published 22 May 2025
10.9734/ajds/2025/v8i1236Abstract
Polycystic ovary syndrome (PCOS) is a multifaceted condition that impacts hormonal balance, fertility, and metabolic function, influencing around 5–15% of women worldwide. Periodontitis (PD) is a persistent inflammatory disease with multiple contributing factors, triggered by a dysbiotic dental plaque, leading to the breakdown of the periodontium—the supporting structures of the teeth. It has been suggested that there may be a bidirectional connection between PCOS and periodontal diseases. Both conditions share common risk factors such as chronic systemic inflammation, insulin resistance, and oxidative stress. Periodontal diseases are worsened by Chronic mild inflammation linked to PCOS encompasses factors such as excess body weight, ongoing immune dysregulation, and elevated oxidative stress. Thus, this review will concentrate on the connection between PCOS and periodontal diseases, along with the shared risk factors for both conditions.
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