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Research Article Open access CC BY 4.0

Oral and Facial Manifestations as Early Indicators of Systemic Sclerosis: A Case Report

Patel Malavika, Parihar Ajay, Reddy Prashanthi, Khairwar Ankita, Toko Bijum

Journal of Advances in Medicine and Medical Research · pp. 102–107 · Published 5 Jan 2026

10.9734/jammr/2026/v38i16044

Abstract

Aim: In order to facilitate prompt diagnosis and referral, it is important to emphasize the part dentists play in the early detection of oral and facial signs of systemic sclerosis (SSc). Presentation of the Case: A 20-year-old girl complained of dental issues and oral discomfort. A clinical examination showed signs of a connective tissue condition, including sclerodactyly, xerostomia, microstomia, and face telangiectasia. Limited cutaneous systemic sclerosis (CREST syndrome) was confirmed by serological testing for anticentromere antibodies. At presentation, there was no obvious systemic organ involvement. Discussion: Microvascular dysfunction and fibrosis are hallmarks of the uncommon autoimmune disease known as systemic sclerosis. Dental assessment is essential for early detection since oral and facial features can emerge early and precede systemic signs. Conclusion: Early identification of oro-facial symptoms by dental professionals improves patient outcomes by enabling timely diagnosis, referral, and multidisciplinary care.

Microvascular systemic sclerosis oral and facial manifestations dental

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