Potential Strategies in Treating Tumours
Venkata Narasimha Kadali, Joyeeta Mitra, Sheji Chandran, Teena Sajan, Smitha Murthy
Asian Journal of Biology · pp. 1–11 · Published 5 Apr 2018
10.9734/AJOB/2018/39869Abstract
Cancer, an absolute sickness exemplified merely by uncontrolled cell proliferation, has always been a concern for universal well-being. The recurrence of cancer is, in fact, mounting globally and fatality rate resulting from this malady is markedly high. Besides genetic alterations, epigenetic modifications also play a vital role in Cancer advancement. Advancements in genomics and proteomics studies enabled researchers to search potential drug targets leading to molecular therapeutics, for instance, Atezolizumab, Nivolumab, Pembrolizumab. This article discusses the potential role of some approaches in treating tumours such as free Hyaluronidase, Hsp90 Inhibitors, Liposomes, Anti–Angiogenesis agents, Apoptosis Proteins Inhibitors, Histone deacetylases inhibitors, Nanomedicine, Blockade of PD‑1/PD‑L1 pathway.
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