Phytochemical Screening and Evaluation of the Antioxidant Activity of Ficus capreifolia Leaf Extract via in-vitro Models
Tetam Jack Gbenenee, Ndokiari Boisa, Tebekeme Okoko
International Journal of Biochemistry Research & Review · pp. 1–7 · Published 2 Jun 2017
10.9734/IJBCRR/2017/34138Abstract
Aims: To carry out preliminary phytochemical screening and determine the antioxidant ability of Ficus capreifolia leaf extract. Study Design: The study was designed to evaluate the phytochemical profile of Ficus capreifolia leaf and the potential antioxidant activity and comparing to reference antioxidant vitamin C. Place and Duration of Study: The research was done in the Department of Chemistry, Rivers State University from May to August 2016. Methodology: The extract was screened for the presence of some phytochemicals. Thereafter, the antioxidant potential was determined by assessing the hydrogen peroxide scavenging ability, hydroxyl radical scavenging activity and ferrous ion reducing ability and comparing them to the corresponding ability of vitamin C. Results: Phytochemicals detected include tannins, carotenoids, alkaloids, flavonoids, steroids, cardiac glycosides and polyphenols. The extract also scavenged hydrogen peroxide, hydroxyl radicals and also reduced ferrous ions significantly when compared to vitamin C. Conclusion: The leaf extract exhibited significant antioxidant activities which could be ascribed to antioxidant phytochemicals such as flavonoids, polyphenols which were detected. This corroborates the reported traditional use of the plant and can be further exploited pharmacologically.
References (29)
- 1 Oxidative Stress and Antioxidant Defense [DOI]
- 2 Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases [DOI]
- 3 Phytochemical constituents of some Nigerian medicinal plants [DOI]
- 4 Antioxidants in Human Health and Disease [DOI]
- 5 A novel automated method to measure total antioxidant response against potent free radical reactions [DOI]
- 6 Antioxidant activity of carotenoids [DOI]
- 7 Redox- and non-redox-metal-induced formation of free radicals and their role in human disease [DOI]
- 8 New concepts in reactive oxygen species and cardiovascular reperfusion physiology [DOI]
- 9 Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis [DOI]
- 10 Reactive oxygen species in tumorigenesis.
- 11 Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer [DOI]
- 12 Antioxidant activities of Salvia miltiorrhiza and Panax notoginseng [DOI]
- 13 Savanna fire and the origins of the ‘underground forests’ of A frica [DOI]
- 14 Rapid determination of flavonoids and phenolic acids in grape juices and wines by RP-HPLC/DAD: Method validation and characterization of commercial products of the new Brazilian varieties of grape [DOI]
- 15 Structural features and antioxidant activity of tannin from persimmon pulp [DOI]
- 16 Antioxidant activity of bisbenzylisoquinoline alkaloids from Stephania rotunda: cepharanthine and fangchinoline [DOI]
- 17 Troxerutin, a plant flavonoid, protects cells against oxidative stress-induced cell death through radical scavenging mechanism [DOI]
- 18 A Quinolone Alkaloid with Antioxidant Activity from the Aleurone Layer of Anthocyanin-Pigmented Rice [DOI]
- 19 Evaluation of the inhibition of carbohydrate hydrolysing enzymes, antioxidant activity and polyphenolic content of extracts of ten African Ficus species (Moraceae) used traditionally to treat diabetes [DOI]
- 20 Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress [DOI]
- 21 FREE RADICAL GENERATION BY METHYLGLYOXAL IN TISSUES [DOI]
- 22 Curcumin protects mouse neuroblastoma Neuro-2A cells against hydrogen-peroxide-induced oxidative stress [DOI]
- 23 Reduction of hydrogen peroxide–induced erythrocyte damage by Carica papaya leaf extract [DOI]
- 24 Radical scavenging propensity of Cu 2+ , Fe 3+ complexes of flavonoids and in-vivo radical scavenging by Fe 3+ -primuletin [DOI]
- 25 Antioxidant and antimicrobial activities of aqueous extract of Withania somnifera against methicillin-resistant Staphylococcus aureus
- 26 Oxidative Stress and Antioxidant Protection [DOI]
- 27 In-vitro antioxidant properties of the hydro-methanol extract of the seeds of Swietenia mahagoni (L.) Jacq. [DOI]
- 28 Simultaneous photoinduced generation of Fe 2+ and H 2 O 2 in rivers: An indicator for photo-Fenton reaction [DOI]
- 29 Mutagenesis of the supF Gene of pSP189 Replicating in AD293 Cells Cocultivated with Activated Macrophages: Roles of Nitric Oxide and Reactive Oxygen Species [DOI]
Cited by 6
Tetam, Jack Gbenenee, Wegwu, Matthew Owhonda, Ikewuchi, Catherine Chidinma · Journal of Applied Life Sciences International · 2021
Tebekeme Okoko, Daniel I. Silas-Olu · Asian Journal of Research in Biochemistry · 2021
J. Tetam, Matthew Owhonda Wegwu, Catherine Chidinma Ikewuchi · Asian Journal of Environment & Ecology · 2021
Showing 3 of 6 known citations — external sources report more than can currently be individually listed.
Related research
- Nutrient Analysis and Antimicrobial Activities of the Leaves and Fruit Pulp Extracts of Tetrapluera tetraptera on Clinical Bacteria Isolates — shares topic coverage
- Antibacterial and Phytochemical Activity of Gliricidia sepium against Poultry Pathogens — shares topic coverage
- Antibacterial Screening of Two Indigenous Nigerian Spices; Piper guineense and Xylopia aethiopica — shares topic coverage
- In vitro Antibacterial Activity of the Extracts of Peperomia pellucida (L) — shares topic coverage
- Phytochemical and Antibacterial Investigation of Leaf Extracts of Vernonia amygdalina — shares topic coverage
Article metrics
Real usage data collected on this platform.
57
Page views
0
PDF downloads
23
Outbound clicks
6
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.