Nocardiosis Associated with Novel Agents at Relapsed Multiple Myeloma: Case Series
Atakan Turgutkaya, Zahit Bolaman, Emel Ceylan, Murat Telli, Berna Gültekin Korkmazgil, Can Karaman, Irfan Yavasoglu
International Blood Research & Reviews · pp. 1–7 · Published 30 Oct 2019
10.9734/ibrr/2019/v10i130111Abstract
Nocardiosis is a gram positive bacterial infection caused by aerobicactinomycetes. It’s nonspesific presentation and radiographic findings usually make it undiagnosed with highly fatal outcomes. The patients with intracelluler defects are prone to nocardiosis. Multiplemyelom(MM) itself is a mainly humoral deficiency disorder because of defective antibodies but recent drugs such as proteasome inhibitors and immuno modulatory drugs also cause cellular deficiency. Here we presented two definite and oneprobable pulmonary nocardiosis patients who have a diagnosis of MM, autologou shematopoetic stem cell transplant history in their past and anti myeloma therapy presently.
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