Post-COVID-19 Multisystem Inflammatory Syndrome: A Cross - Sectional Retrospective Study

Abstract

Aims: To verify if children hospitalized by COVID-19, met the criteria for Multisystem Inflammatory Syndrome. Study Design: Quantitative, retrospective cohort, retrolective. Place and Duration of Study: Sample: All registries from Guanajuato General Hospital of patients with less than 21 years old with diagnosis of COVID-19, from April 2020 to December 2023. Methodology: It was obtained 664 registries from hospitalized patients with an admission diagnosis of COVID-19; 27 records corresponded to patients under 21 years of age, and one of these records was eliminated due to the lack of a positive COVID-19 result. The CDC criteria for Multisystem Inflammatory Syndrome in children was applied in the 26 records; also it was collected, sex, age, co-morbidities, days of positive SARS-CoV-2 test and days hospitalized. It was calculated Chi-squared test and OR (95% CI) with logistic regression. Results: 3 from 26 (11.54%) children fulfilled the CDC criteria for Multisystem Inflammatory Syndrome in children, mainly fever ≥38°C (100%), the severity of the case required hospitalization (100%), cardiac involvement (0%), 2 had inflammation of oral mucosa (66.67%), 2 had abdominal pain (66.67%), 1 vomiting (33.33%), 2 had platelet count ≤ 150,000 cells/µL (66.67%). The Chi-squared test and logistic regression were no significative (P >.05) between sex, age, co-morbidties, days with COVID-19, and days hospitalized. Conclusion: The frequency of Multisystem Inflammatory Syndrome in children was higher that reported in another places. The sample size was short and probably for this, the non-significative of the results.