Review on Transferosomes and Transferosomal Gels
P. Kranthi Kumar, R. Santosh Kumar
Journal of Pharmaceutical Research International · pp. 114–126 · Published 9 Sep 2021
10.9734/jpri/2021/v33i43B32532Abstract
Transdermal drug delivery systems (TDDS), which are self-administrable and non-invasive, can improve bioavailability and patient compliance by bypassing first-pass metabolism. Vesicular-based TDDS have attracted a lot of attention in recent years because they're designed for controlled, efficient, and targeted drug delivery. One of these delivery technologies, transferosomal-based formulations, has grown in popularity due to its ability to achieve all of the desired criteria and quality qualities. Transferosomes combine the characteristics of liposomes and niosomes because they contain both liposomes (phospholipids and cholesterols) and niosomes as components (nonionic surfactants; edge activators). as a result, they are referred to as the first generation of elastic liposomes. However transdermal drug delivery is difficult due to the presence of the skin's protective barrier, transferosomal drug delivery overcomes all obstacles due to its unique characteristics, such as its ultradeformable vesicular nature. The benefits, limitations, modes of penetration, formulations, production and assessment methodologies, and pharmaceutical uses of transferosomal drug delivery systems are discussed in this paper. Conclusion: Transferosomes have several importance over other vesicular systems, including greater deformability, greater penetration power across skin, the ability to deliver systemic drugs, and higher stability.
Cited by 16
Bhupendra Dixena, Rashmi Madhariya, Anupama Panday · Current Drug Delivery · 2025
Kariman M AbouElhassan, Hatem A Sarhan, Amal K Hussein · International Journal of Nanomedicine · 2022
Akshay Kumar, Balak Das Kurmi, Amrinder Singh · Exploration of Targeted Anti-tumor Therapy · 2022
D. MAHESWARA REDDY, MOTHILAL M. · International Journal of Applied Pharmaceutics · 2024
Kateryna Mykhailivna Doroshenko, Oleksander Ivanovich Shefchenko · Bioorganic & Medicinal Chemistry Letters · 2025
Kateryna Mykhailivna Doroshenko, Oleksandr Ivanovych Shevchenko · Biotechnology Journal · 2026
Hui Xing, Ziyi Zhao, Xiaoxu Zhu · MedComm – Biomaterials and Applications · 2025
Jaydeep Jagannath Chemate, Pravin Shridhar Wakte, Sachin Shivling Bhusari · Journal of Drug Delivery and Therapeutics · 2026
Pavuluri Chandrasekhar, Rajaganapathy Kaliyaperumal · Recent Advances in Drug Delivery and Formulation · 2024
Anshu Singh, Zeeshan Fatima, Dipti Srivastava · Current Drug Delivery · 2025
Showing 13 of 16 known citations — external sources report more than can currently be individually listed.
Related research
- Bioavailability of Plastic Contaminants and Their Effects on Plastic Bottled and Sachet Drinking Water Supplies — shares topic coverage
- Bioavailability and Toxicity of Plastic Contaminants to Soil and Soil Bacteria — shares topic coverage
- Antinutrients and Bioavailability of Nutrients in Maize, Cassava and Soybeans Composite Flour — shares topic coverage
- Production and Evaluation of Breakfast Meals from Germinated and Ungerminated Blends of Sorghum and Soybean by Cold Extrusion Process — shares topic coverage
- Organic Minerals in Poultry — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
16
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.