Robust Healthcare AI Frameworks Mitigating Adversarial Attacks and Personal Data Stress Anxiety

Abstract

This study presents a hybrid federated learning and explainable artificial intelligence framework, termed RobustFL, designed to mitigate adversarial attacks in medical imaging while incorporating privacy-preserving mechanisms. Focusing on chest X-ray analysis, the research systematically examined adversarial vulnerabilities and data privacy challenges in distributed healthcare systems. A simulation-based methodology was implemented using a 500-sample dataset partitioned across multiple clients in a non-independent and identically distributed setting. The framework extends federated averaging by integrating projected gradient descent-based adversarial training, differential privacy stochastic gradient descent, and SHAP-based interpretability. Experimental results demonstrate that RobustFL maintains stable performance under adversarial conditions, achieving 70% accuracy against FGSM and PGD attacks, with an adversarial success rate of approximately 30–31%. A balanced privacy budget of ε = 1.0 produced an F1-score of 0.412, indicating a trade-off between privacy and model utility. Interpretability consistency, measured via SHAP outputs, served as a proxy for trust assessment, while privacy risk indicators were used to infer potential user concern. The framework provides a practical pathway toward secure, transparent, and privacy-aware healthcare AI systems.