Role of Curcuma Longa in Type 2 Diabetes and its Associated Complications

Abstract

Background: Occurrence of Diabetes and its related complications increased all over the world due to recent lifestyle trends.  A higher proportion of ultra-processed foods in the diet have been associated with a higher risk of T2D. A lack of fiber and a surplus of refined simple carbohydrate are contributing to obesity and diabetes diagnosis. Hence there is need to evaluate different nutraceuticals for the management of Diabetes. Methodology: A Scopus, pub Med/Medline and Google Scholar electronic database search was done by using the key word role of Curcuma Longa in diabetes type 2 and its associated complications to review the related articles. Summary: Curcumin a yellow color powder is one of the most important components of Curcuma Longa L; and commonly utilized as food additive in Asian countries. Pre-treatment of human umbilical vein endothelial cells curcumin leads to decrease in intracellular MGO level induced by exogenous MGO and also modify the carboxymethyl cellulose formation. Curcumin nutritional supplement fully normalized arterial AGEs. Curcumin reduced AGEs increase in the heart of diabetic rats. Curcumin reduces the development of diabetes in pre-diabetic population. Conclusion: The literature review shows that the Curcuma Longa L; revealed anti-diabetic and antioxidant effects and prevent the development of diabetes associated complications in different animal model.