Leukemia Cutis as an Isolated Extra-medullary Blast Crisis in Chronic Myeloid Leukemia: A Rare Case Report
Suprotim Ghosh, Subhra Kamal Saha, Prakas Kumar Mandal, Shuvra Neel Baul
Asian Hematology Research Journal · pp. 300–304 · Published 9 Dec 2025
10.9734/ahrj/2025/v8i4224Abstract
Leukemia Cutis, characterized by infiltration of skin by leukemic cells leading to clinically recognizable cutaneous lesions, is a rare manifestation found in various underlying leukemias and sometimes as sole presentation. Its presence often correlates with underlying advanced stages of the disease and invariably associated with a dismal prognosis. Moreover, cutaneous leukemic proliferations often pose a diagnostic challenge. In this article, we report a rare case of biopsy proven leukemia cutis in a patient of chronic myeloid leukemia without bone marrow or other organ involvement, successfully treated with intensive chemotherapy. We emphasize the importance of early clinical identification, pathological diagnosis and apt initiation of definitive therapy.
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