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Research Article Open access CC BY 4.0

Study on Serum Zinc Levels and Vitamin a Levels in Tuberculosis Patients

Gangaram Bhadarge, Nandkishor Bankar, Sudhir Singh

Journal of Pharmaceutical Research International · pp. 40–44 · Published 13 Jul 2021

10.9734/jpri/2021/v33i37A31977

Abstract

Introduction: Tuberculosis, an infectious disease caused by the bacteria Mycobacterium tuberculosis (MTB), is also a major cause of death in humans around the world. According to a World Health Organization (WHO) survey, MTB infects one-third of the world's population, with 9.6 million new tuberculosis (TB) infections and 1.5 million deaths confirmed this in 2021 Aim: study of serum zinc levels and vitamin a levels in tuberculosis patients. Materials and Methods: This study included 40 newly diagnosed PTB patients of both sex with the age group of 18-60.Time period of this study was from September 2020 to Арril 2021 а nоn-rаndоmised соntrоlled trial was involved. Result: There was a strong correlation between serum zinc and vitamin A levels P < 0.01) Hb, P < 0.01) and serum albumin levels P < 0.01) were also strongly correlated with the vitamin A levels; however, WBC P < 0.01) and ESR P < 0.01) were negatively correlated with the vitamin A levels. Conclusion: In view of the above, the patient's nutritional status may be the most important determinant of infection tolerance. Zinc deficiency can have an indirect impact on Vitamin A metabolism by reducing the levels of circulating protein. Because of this, the addition of zinc in combination with vitamin A may be helpful in achieving the disease status.

MTB Vit-A Zinc Retinol Micronutrient

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