Minireview of Stereoselective Brain Imaging

References (81)

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12. 12 Effect of the alpha-2 adrenoceptor antagonist mirtazapine on the 5-hydroxytryptamine system in the rat brain. [DOI]
13. 13 Vesicular monoamine transporter 2: Role as a novel target for drug development [DOI]
14. 14 (R)- and (S)-[11C]verapamil as PET-tracers for measuring P-glycoprotein function: in vitro and in vivo evaluation [DOI]
15. 15 Recent progress in alpha1-adrenergic receptor research [DOI]
16. 16 Neuroprotective effect of estrogen: Role of nonsynaptic NR2B-containing NMDA receptors [DOI]
17. 17 Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl, (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and PET studies in baboon brain [DOI]
18. 18 Optical Isomerism and Pharmacological Action, a Generalization [DOI]
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21. 21 Rapid Stereoselective Hydrolysis of (+)‐Cocaine in Baboon Plasma Prevents Its Uptake in the Brain: Implications for Behavioral Studies [DOI]
22. 22 Radioligand studies: imaging and quantitative analysis [DOI]
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26. 26 Ketamine Stereoselectively Inhibits Spontaneous Ca2+-Oscillations in Cultured Hippocampal Neurons [DOI]
27. 27 Synthesis and in vitro characterization of trans- and cis-[18F]-4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]-3-fluoropiperidine-1-carboxylates as new potential PET radiotracer candidates for the NR2B subtype N-methyl-d-aspartate receptor [DOI]
28. 28 Development of novel PET probe [11C](R,R)HAPT and its stereoisomer [11C](S,S)HAPT for vesicular acetylcholine transporter imaging: A PET study in conscious monkey [DOI]
29. 29 Decreased uptake and binding of11C-nicotine in brain of Alzheimer patients as visualized by positron emission tomography [DOI]
30. 30 Uptake and regional distribution of (+)-(R)- and (−)-(S)-N-[methyl-11C]-nicotine in the brains of Rhesus monkey an attempt to study nicotinic receptors in vivo [DOI]
31. 31 Effects of aging on serotonin transporter availability and its response to fluvoxamine in the living brain: PET study with [11C](+)McN5652 and [11C] (‐)McN5652 in conscious monkeys [DOI]
32. 32 Brain kinetics of (R)- and (S)-[N-methyl-11C]ketamine in the rhesus monkey studied by positron emission tomography (PET) [DOI]
33. 33 Fluoro analogs of WAY-100635 with varying pharmacokinetics properties [DOI]
34. 34 Binding potential of (E)-[11C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its 11C-labelled Z-isomer [DOI]
35. 35 Highlights of PET studies on chiral radiotracers and drugs at Brookhaven [DOI]
36. 36 Pharmacokinetic and pharmacodynamic consequences of stereoselective drug metabolism in man [DOI]
37. 37 Quantitative autoradiography of brain binding sites for the vesicular acetylcholine transport blocker 2-(4-phenylpiperidino)cyclohexanol (AH5183). [DOI]
38. 38 Antinociceptive effects of the stereoisomers of nicotine given intrathecally in spinal rats [DOI]
39. 39 Enantiomers: how valid is Pfeiffer's rule? [DOI]
40. 40 The pattern of [3H]cyclofoxy retention in rat brain after in vivo injection corresponds to the in vitro opiate receptor distribution [DOI]
41. 41 Transport across the blood-brain barrier: stereoselectivity and PET-tracers [DOI]
42. 42 Kinetic analysis of the opiate antagonist cyclofoxy in rat brain: simultaneous infusion of active and inactive enantiomers. [DOI]
43. 43 Stereoselective neuroimaging in vivo [DOI]
44. 44 PET neuroimaging of [11C]mirtazapine enantiomers in pigs [DOI]
45. 45 Positron emission tomography of 5-HT reuptake sites in the human brain with C-11 McN5652 extraction of characteristic images by artificial neural network analysis [DOI]
46. 46 Uptake and distribution of a new SSRI, NS2381, studied by PET in living porcine brain [DOI]
47. 47 Effects off pyrroloisoquinoline enantiomers ((+)- and (-)-McN-5652-Z) on behavioral and pharmacological serotonergic mechanisms in rats [DOI]
48. 48 Assessment of brain muscarinic acetylcholinergic receptors in living mice using a simple probe, [125I]-4-iododexetimide and [125I]-4-iodolevetimide [DOI]
49. 49 Active and inactive enantiomers of 2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: comparison using homogenate binding and single photon emission computed tomographic imaging. [DOI]
50. 50 Neuroimaging of mirtazapine enantiomers in humans [DOI]
51. 51 Simplified Reference Tissue Model for PET Receptor Studies [DOI]
52. 52 Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice [DOI]
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55. 55 PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain [DOI]
56. 56 11C-GR103545, a radiotracer for imaging kappa-opioid receptors in vivo with PET: synthesis and evaluation in baboons.
57. 57 Pet study of [11C] β‐CIT binding to monoamine transporters in the monkey and human brain [DOI]
58. 58 Human dopamine receptor subtypes?in vitro binding analysis using3H-SCH 23390 and3H-raclopride [DOI]
59. 59 In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain [DOI]
60. 60 Tacrine restores cholinergic nicotinic receptors and glucose metabolism in alzheimer patients as visualized by positron emission tomography [DOI]
61. 61 PET studies of the uptake of (S)- and (R)-[11C]nicotine in the human brain: difficulties in visualizing specific receptor binding in vivo [DOI]
62. 62 Pharmacological effects of epibatidine optical enantiomers [DOI]
63. 63 Evaluation of a new norepinephrine transporter PET ligand in baboons, both in brain and peripheral organs [DOI]
64. 64 Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER [DOI]
65. 65 Brain kinetics of methylphenidate (Ritalin) enantiomers after oral administration [DOI]
66. 66 Quantification of brain phosphodiesterase 4 in rat with (R)-[11C]Rolipram-PET [DOI]
67. 67 [11C]-GR89696, a potent kappa opiate receptor radioligand; in vivo binding of the R and S enantiomers [DOI]
68. 68 Synthesis and in vivo biodistribution of F-18 labeled 3-cis-, 3-trans-, 4-cis-, and 4-trans-fluorocyclohexane derivatives of WAY 100635 [DOI]
69. 69 An in vivo comparison of cis- and trans-[18F]mefway in the nonhuman primate [DOI]
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71. 71 Carbon-11-d-threo-methylphenidate binding to dopamine transporter in baboon brain.
72. 72 Behaviour of [11C]R(−)‐ and [11C]S(+)‐rolipram in vitro and in vivo, and their use as PET radiotracers for the quantificative assay of PDE4 [DOI]
73. 73 Radiolabelling of 1,4-disubstituted 3-[18F]fluoropiperidines and its application to new radiotracers for NR2B NMDA receptor visualization [DOI]
74. 74 STEREOSPECIFIC IN VlTRO BINDING OF [3H]DEXETIMIDE TO BRAIN MUSCARINIC RECEPTORS [DOI]
75. 75 Synthesis and in vivo studies of the stereoisomers of N-[11C]methyl-homoepibatidine [DOI]
76. 76 New synthesis and evaluation of enantiomers of 7-methyl-2-exo-(3′-iodo-5′-pyridinyl)-7-azabicyclo[2.2.1]heptane as stereoselective ligands for PET imaging of nicotinic acetylcholine receptors [DOI]
77. 77 In vivo detection of short‐ and long‐term MDMA neurotoxicity—a positron emission tomography study in the living baboon brain [DOI]
78. 78 Synthesis and evaluation of racemic [11C]NS2456 and its enantiomers as selective serotonin reuptake radiotracers for PET [DOI]
79. 79 BBB transport and rapid tissue binding of cyclofoxy: comparison of active and inactive enantiomers [DOI]
80. 80 Stereoselective effects of cocaine [DOI]
81. 81 McN-5652: a highly potent inhibitor of serotonin uptake. [DOI]

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