Anti-inflammatory Activity and In silico Approaches on Root Extract of Decalepis hamiltonii Wight & Arn
Palanisamy Prakash, Rengarajan Manivasagaperumal
Journal of Pharmaceutical Research International · pp. 1–8 · Published 16 Aug 2017
10.9734/JPRI/2017/32070Abstract
Aims: The present study was aimed to evaluate anti-inflammatory and antioxidant potential of methanol root extract of Decalepis hamiltonii. Results: The methanolic extract showed in vitro anti-inflammatory activity inhibition cells 96.1%µg/ml. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay was significant inhibited by the methanol (96.2) and inhibition addition the Nitric oxide production 25 µg/ml 95% inhibition. The methanol extract of Decalepis hamiltonii shows a Thus, a very strong approach to In-silico docking and in vitro anti-inflammatory study for whole with these compounds/extract. Conclusion: From the study it is concluded that the root extract of Decalepis hamiltonii showing a strong approach to In-silico docking and anti inflammatory activity.
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