The Manifestations of Macrophage Activation Syndrome: A Case Report
Mandana Khodashahi, Zahra Mirfeizi, Naser Tayyebi Meibodi, Mohammad Reza Hatef
International Journal of Medical and Pharmaceutical Case Reports · pp. 1–6 · Published 23 Aug 2015
10.9734/IJMPCR/2015/18921Abstract
Introduction: Macrophage Activation Syndrome (MAS) is a rare and life-threatening complication of various chronic rheumatic diseases. It is associated with systemic-onset juvenile idiopathic arthritis (SoJIA). Case Report: A 19-year old woman was referred to our hospital with a history of fever, sweating, anorexia, and pancytopenia, due to her persistent fever; she was admitted in the infectious disease department. Bone marrow aspiration and biopsy findings were suggestive for MAS associated with SoJIA or Still's disease. She showed a remarkable response to treatment after Hydrocortisone and cyclosporine. Conclusion: MAS can occur within a few days after overt manifestations of the primary disease. Our patient developed MAS symptoms rapidly. MAS might be predictor to rheumatic diseases.
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