The p53 Codon 72 Polymorphism in Moroccan Women and the Risk of Ovarian Cancer
Mustapha Benhessou, Samira Zoa Assoumou, Luc Magloire Anicet Boumba, Said Bouhya, Mohammed Nabil Benchekroun, My Mustapha Ennaji
Microbiology Research Journal International · pp. 1–5 · Published 2 Dec 2015
10.9734/BMRJ/2016/22295Abstract
The aim of this study was to examine the association of the p53 codon 72 polymorphism with ovarian carcinoma development in Moroccan women. Samples from 44 women with ovarian cancer and 80 healthy controls, were used. p53 codon 72 polymorphism determination was performed by allele-specific PCR assay. The distribution of Arg/Arg, Arg/Pro and Pro/Pro genotypes was 33/44 (75%), 10/44 (22.7%) and 1/44 (2.3%) in the cervical cancer group and 43/80 (53.8%), 27/80 (33.7%) and 10/80 (12.5%) in the control group. No significant association was found between polymorphism of p53 and risk of development of ovarian cancer among Moroccan women. Thus, the polymorphism of p53 codon 72 in exon 4 does not seem to play a role in the development of ovarian cancer among Moroccan women.
Cited by 1
Anqi Zhang, Tingyan Shi, Yuan Zhao · OncoTarget · 2017
Related research
- - 251 A/T Single Nucleotide Polymorphism of Interleukin 8 and Susceptibility to Acute Myocardial Infarction — shares topic coverage
- Exploring Genetic Variability among Mutant Accessions of Arabidopsis thaliana L. — shares topic coverage
- Study of -141 DRD2 Dopamine Receptor Gene Polymorphism (rs1799732) and Heroin Dependence — shares topic coverage
- Frequencies of Genotypes and Alleles of the K232A Substitution in the DGAT1 Gene in Four Cattle Breeds of Russian Selection — shares topic coverage
- Database Derived Microsatellite Markers (SSRs) of Stevia rebaudiana for Cross-transferability Testing Across Species in Family Asteraceae — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
1
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.