The Prevalence of Metabolic Syndrome of Patients on Treatment with Haloperidol and Risperidone or Olanzapine
Velumani Suresh, J. D. Lakhani, Rakesh Shah, Lakhan Kataria, Ramachandran Balaraman
Journal of Pharmaceutical Research International · pp. 320–327 · Published 18 Sep 2021
10.9734/jpri/2021/v33i44A32618Abstract
Background: The background of the work stems from the observation due to the prevalence of antipsychotic drugs in causing metabolic disorder. The metabolic disorder is one of the major concern of antipsychotic drugs for schizophrenic patients. The present study is mainly aimed to establish the role of haloperidol and risperidone or olanzapine in causing metabolic syndrome of schizophrenic patients. Methods: Sixty-four schizophrenic patients were divided into two groups. First and second group received haloperidol and risperidone or olanzapine respectively for three months. Body mass index, random blood sugar and lipid profile were investigated before and after the treatment. Results: Both groups of schizophrenic patients have shown a significant increase in the BMI, random blood sugar and lipid profile indicating a propensity to cause metabolic disorder. Conclusion: From the present study it is concluded that there is a high prevalence of metabolic disorder those who received antipsychotic drugs like haloperidol and risperidone or olanzapine.
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Velumani Suresh, J. D Lakhani, Ramachandran Balaraman · Journal of Natural Remedies · 2022
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