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Research Article Open access CC BY 4.0

Transient Anti PM-Scl75 Antibody Positive Acral Ischemia Syndrome in a 15 Years-Old Girl

Stefan Bittmann, Elisabeth Luchter, Elena Moschüring-Alieva

Asian Journal of Pediatric Research · pp. 37–43 · Published 13 Mar 2024

10.9734/ajpr/2024/v14i3332

Abstract

In 1862, the French doctor Maurice Raynaud published his dissertation in Paris titled "Sur l’asphyxie locale et la gangrène symétrique des extrémités" (On local asphyxia and symmetrical gangrene of the extremities). In it, he described a series of cases in which there were episodes of acral ischemia. The phenomenon later named after him typically involves changes in skin color from white to blue-livid to red, caused by a vasospasm of acral arteries (white phase) followed by reactive vasodilation. Acral ischemia is present in different clinical conditions as stated in this manuscript. We report a case of a transient anti PM-Scl75 antibody positive acral ischemia syndrome in a 15 years-old girl.

Thrombosis embolism blockage oxygen deprivation ischemia

References (32)

  1. 1 Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers [DOI]
  2. 2 Assessment of Acute Acral Lesions in a Case Series of Children and Adolescents During the COVID-19 Pandemic [DOI]
  3. 3 Novel aspects of autoantibodies to the PM/Scl complex: Clinical, genetic and diagnostic insights [DOI]
  4. 4 Raynaud’s phenomenon: Current concepts [DOI]
  5. 5 Acral vascular necrosis associated with immune-check point inhibitors: case report with literature review [DOI]
  6. 6 Clinical Significance of Antinucleolar Antibodies: Biomarkers for Autoimmune Diseases, Malignancies, and others [DOI]
  7. 7 “COVID toes”: A true viral phenomenon or a diagnosis without a leg to stand on? [DOI]
  8. 8 PM–Scl‐75 is the main autoantigen in patients with the polymyositis/scleroderma overlap syndrome [DOI]
  9. 9 Rapid improvement in digital ischemia and acral contracture in a collodion baby treated with topical tazarotene.
  10. 10 The prevalence and significance of anti-PM/Scl antibodies in systemic sclerosis [DOI]
  11. 11 Acral coldness – severely reduced blood flow to fingers and toes [DOI]
  12. 12 Top 10 acral skin manifestations associated with COVID ‐19: A scoping review [DOI]
  13. 13 Acral lesions in a pediatric population during the COVID-19 pandemic: a case series of 36 patients from a single hospital in Spain [DOI]
  14. 14 Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex. [DOI]
  15. 15 Ischemia of Postmastectomy Skin After Infiltration of Local Anesthetic with Epinephrine: A Case Report and Review of the Literature [DOI]
  16. 16 Rash Morphology as a Predictor of COVID-19 Severity: A Systematic Review of the Cutaneous Manifestations of COVID-19 [DOI]
  17. 17 Paraneoplastic acral vascular syndrome: case presentation and literature review [DOI]
  18. 18 Childhood Scleromyositis: An Overlap Syndrome Associated with PM‐Scl Antibody [DOI]
  19. 19 Capillary Microscopy Is a Diagnostic Aid in Patients with Acral Ischemia [DOI]
  20. 20 Digital Ischemia as an Unusual Manifestation of Hodgkin’s Lymphoma [DOI]
  21. 21 Acute Limb Ischemia: A Catastrophic COVID-19 Sequel Leading to Amputation [DOI]
  22. 22 [Acral ischaemia with multiple microthromboses and imminent gangrene in a 73-year-old woman with COVID-19].
  23. 23 Acral vascular syndrome Lennert type T cell lymphoma—a case report [DOI]
  24. 24 Management of a Child vs an Adult Presenting With Acral Lesions During the COVID-19 Pandemic: A Practical Review [DOI]
  25. 25 PM/Scl overlap syndrome in a 14‐year‐old girl manifesting after a SARS‐CoV‐2 infection [DOI]
  26. 26 Painful ANA-Positive Scleroderma-Like Disease With Acral Ulcerations: A Case of Chronic Gangrenous Ergotism [DOI]
  27. 27 Isquemia acral secundaria a feocromocitoma [DOI]
  28. 28 Acral ischemia induced by nivolumab: A case report [DOI]
  29. 29 Acute Digital Ischemia Associated with Closed Injury [DOI]
  30. 30 Acral ischemia as a presenting manifestation of essential thrombocythemia [DOI]
  31. 31 Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers [DOI]
  32. 32 PM/Scl‐Overlap‐Syndrom bei einem 14‐jährigen Mädchen nach SARS‐CoV‐2‐Infektion [DOI]

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