Assessment of Thrombolytic Activity of Selected Species from Lamiaceae Family Growing Naturally in Kurdistan Region\Iraq Using In-vitro Model
Journal of Advances in Medical and Pharmaceutical Sciences · pp. 1–5 · Published 6 Oct 2015
10.9734/JAMPS/2015/20550Abstract
Aims: The present study was aimed to assess most commonly used medicinal plant belong to Lamiaceae family for their thrombolytic activity. Place and Duration of the Study: Pharmacy College\ Hawler Medical University, June, 2015. Methodology: Dried leaf part ethanolic extracts of selected species have been evaluated for their thrombolytic activity using fresh human blood specimen at concentrations of 200, 400, 600, 800 and 1000 µg\ml, streptokinase drug and distilled water were incorporated in the study as control positive and negative, respectively. Results: Showed significant thrombolytic activity of leaf extracts at all tested concentrations in comparison with control negative distilled water (P < 0.01), highest clot lysis activity were recorded for Salvia officinalis leaf extract (68.43±1.457%) and minimum activity were exhibited by Rosmarinus officinalis leaf extract (49.27±3.256%). Salvia officinalis and Thymus vulgaris expressed significant thrombolytic activity in comparison with control positive streptokinase (P < 0.05) at highest tested dose concentration (1000 µg\ml). Conclusion: Selected species from Lamiaceae plant family can open a venue for production of thrombolytic drugs derived from natural source with greatest activity and lowest adverse effects.
Cited by 0
No indexed citations yet.
Related research
- Antibacterial Activities of Essential Oils from Three Medicinal Plants in Combination with EDTA against Methicillin-resistant Staphylococcus aureus — shares topic coverage
- Effect of Biological, Organic and Chemical Fertilizers on Vegetative Growth, Physiological Characteristics and Essential Oils of (Thymus vulgaris L.) — shares topic coverage
- Effect of Co-administration of Ascorbic Acid (Vitamin C) and Ethanolic Extract of Thymus vulgaris L. on Lipid Profile and Some Liver Function Parameters in Male Wistar Rats — shares topic coverage
- Erectogenic Effect of Thyme (Thymus vulgaris) Extract in Normal and 5-Fluorouracil induced Oxidative Stressed Adult Male Wistar Rats — shares topic coverage
- Investigation of Effects of Ecological Factors on the Establishment of Azotobacter in the Rhizosphere of Thyme (Thymus vulgaris) — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.