Use of Gabapentin as an Adjunct Agent in the Treatment of Neonatal Abstinence Syndrome: A Case Report
Alyssa Brzenski, Mark Greenberg
International Journal of Medical and Pharmaceutical Case Reports · pp. 84–88 · Published 13 Mar 2015
10.9734/IJMPCR/2015/16142Abstract
We report the use of Gabapentin (Neurontin), an anticonvulsant and analgesic, as a non-opioid adjunct agent in the treatment of a term newborn infant with neonatal abstinence syndrome (NAS). Initial treatment with methadone to prevent withdrawal symptoms was not fully effective. Despite the addition of clonidine, an alpha-2 agonist, he was still unable to be weaned off opioids. The addition of gabapentin reduced symptoms, allowing for successful taper off methadone, and discharge from the hospital. As a non-opioid agent, gabapentin is a drug with potential for assisting with the difficult task of treating NAS refractory to standard opioid therapy due to its sedative and analgesic properties without any respiratory depression.
Cited by 5
Hossein Saneian, Peiman Nasri, Ahmad Heydari · Advanced Biomedical Research · 2024
Joseph Asaro, Christine A. Robinson, Philip T. Levy · Child Neurology Open · 2017
Lauren Fleser, Erin Tibbetts, Alison Hanson · The Journal of Pediatric Pharmacology and Therapeutics · 2024
Caroline Patz, Caren Liviskie, Merielle Bird · The Journal of Pediatric Pharmacology and Therapeutics · 2023
Christopher McPherson · Neonatal Network · 2021
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