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Research Article Open access CC BY 4.0

From Confusion to Clarity: Management of Rare and Elusive, KIKUCHI-FUJIMOTO Disease

SUNIL VASUDEV, PRAVEENA A, SARAYU GOPAL, DALLEN SHONE D’MELLO

Asian Journal of Case Reports in Medicine and Health · pp. 147–153 · Published 14 May 2025

10.9734/ajcrmh/2025/v8i1235

Abstract

KIKUCHI-FUJIMOTO disease (KFD), or HISTIOCYTIC NECROTIZING LYMPHADENITIS, is a benign and self-limited disease that mainly affects young women. Patients present with localized lymphadenopathy, fever, and leukopenia in up to half of the cases. It was first described by Dr Masahiro Kikuchi in 1972 and independently by Y. Fujimoto. This article briefs about a case of KFD which was earlier misinterpreted as a space infection and its diagnosis and management. 

KIKUCHI-FUJIMOTO lymphadenopathy fever and leukopenia

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