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Research Article Open access CC BY 4.0

Unusual Presentation of Primary Hypothyroidism

Sandeep Kr. Agarwal, Dipti Sarma, Uma Kaimal Saikia, Bipul Choudhury

Journal of Advances in Medicine and Medical Research · pp. 1–8 · Published 28 Jan 2016

10.9734/BJMMR/2016/23244

Abstract

Primary hypothyroidism may present with myriad of unusual presentation apart from typically described signs and symptoms. We report an unusual case of primary hypothyroidism clinically presenting as acute psychosis and radiologically mimicking as pituitary macroadenoma. A 19-year-old female presented with h/o abnormal behaviour in the form of auditory hallucination, fearfulness, loss of memory and inability to recognise family members six months back. She also gave h/o multiple joint pain, easy fatigability, facial puffiness, somnolence, progressive weight gain, constipation and cold intolerance for similar duration. MRI brain revealed enlarged pituitary, while the thyroid function analysis pointed towards primary hypothyroidism. Patient improved with LT4.

Hypothyroidism psychosis pituitary hyperplasia.

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