Multi-Drug Resistant Campylobacter jejuni of Poultry Origin in Ado-Ekiti, Nigeria

Abstract

The occurrence of Campylobacter jejeni in the large intestine of domestic fowls in Ado-Ekiti was assessed using standard microbiological procedures. One hundred faecal swabs were inoculated into modified cefoperazone charcoal deoxycholate agar (mCCDA). Twenty-seven isolates of Campylobacter jejeni were recovered from the birds. Biochemical identification of the isolates was carried out using oxidase and catalase tests. Antibiotic susceptibility test was carried out using standard disc diffusion method as specified by the Clinical Laboratory Standard Institute (CLSI), to the following antibiotics; amoxicillin, cefoperazone, ceftazidime, aztreonam, ceftriaxone, pefloxacin, ciprofloxacin, levofloxacin, enrofloxacin and norfloxacin. The pattern of resistance was as follows; Amoxicillin (66.7%), cefoperazone (48.1%), ceftazidime (66.7%), aztreonam (40.7%), ceftriaxone (74.15), pefloxacin (51.9%), ciprofloxacin (33.3%), levofloxacin (40.7%), enrofloxacin (22.25) and norfloxacin (59.3%). Twenty-three different multiple resistance pattern were observed among the isolates. The high level resistance observed in this study poses significant health risk to the general public, a synergistic collaboration is therefore suggested between public health policy-makers and researchers to curb this ugly trend.