Evaluation of 1000 Upper Gastrointestinal Endoscopies; Diagnostic Yield and Incidence of H. pylori Infection

Abstract

Aim: To study the incidence of various pathologies in upper gastrointestinal endoscopy (UGIE) and the correlation of the endoscopic findings with histopathological interpretation of the endoscopic biopsies. Incidence of H. pylori bacteria in patients with gastritis was also noted among the patients. Place and Duration of Study: This study includes evaluation of 1000 cases of endoscopy performed over a period of 5 years in Department of Surgery, Jawaharlal Nehru Medical College, Aligarh. Methodology: Upper gastrointestinal endoscopy was done in patients presenting to outpatient clinic with upper gastrointestinal (GI) complaints. Endoscopic findings were noted and biopsy was taken where indicated and sent for histopathological analysis and rapid urease testing. Results: The patients presented with various complaints like chronic upper abdominal pain, dyspepsia, hematemesis etc. Among the 1000 cases, 69.2% had gastritis, 12.4% had duodenitis, 8.8% had esophageal varices, 8.4% had esophagitis, 4.4% had carcinoma esophagus, 3.2% had portal gastropathy, 2.8% had esophageal stricture, 2.8% had duodenal ulcer, 2.8% had gastric ulcer, 2..8% had hiatus hernia and 1.6% had carcinoma stomach . Among the 692 cases tested for H. pylori 52.94% were positive. Conclusion: In our series the most frequently detected upper GI lesions were gastritis and duodenitis. The incidence of H. pylori positive cases is comparable to those of international studies.