Antioxidant, Lipid Peroxidation and Astringency Study of Hydroethanolic Root Extracts of Bergenia ligulata, Bergenia ciliata and Bergenia stracheyi

Abstract

Aims: Hemorrhoid is a painful disorder both physically and mentally. So in the present research article anti-hemorrhoidal activity of hydroethanolic root extract of Bergenia species namely Bergenia ciliata, Bergenia ligulata and Bergenia stracheyi were studied by antioxidant, lipid peroxidation and astringency parameters. Methods: For this UV-spectroscopy method was used. Place and Duration of Study: Work was done in department of Pharmacy, Banasthali University, India, July 2013-July 2015. Methodology: To perform the antioxidant, lipid peroxidation and astringency parameters, total 3 samples of plant extract and 4 standards were selected. All samples were studied at maximum respective absorbance. IC50 value (inhibition at 50% concentration), R2 (regression value) and probability of extracts and standards were calculated at constant and different concentration.  Results: Results showed that extracts are best free radical inhibitor at higher concentration and best mechanism to control the free radical is metal chelating activity. Conclusion: We have successfully tried to find out solution for hemorrhoid by observing the results responsible for this.